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What is Hemiplegic Migraine?

This section will teach you about Hemiplegic Migraine, variations, diagnosis, medications and treatments, and symptoms.

Hemiplegic Migraine Defined

Hemiplegic Migraine (HM) is a rare, neurological disease. HM is classified as migraine with aura accompanied by motor weakness. When a hemiplegic migraine attack occurs, the person can experience a variety of symptoms ranging in severity and lasting in duration from a few minutes to months.

Symptoms can include visual disturbances, sensory loss, weakness to paralysis on one-side of the body, confusion, speech difficulty, impaired consciousness, coma, memory loss, as well as several other symptoms.


Familial Hemiplegic Migraine

Familial Hemiplegic Migraine (FHM) is a variation of Hemiplegic Migraine where at least one first-degree or second-degree relative also has Hemiplegic Migraine.

Currently, there are three subtypes of FHM: FHM1-FM3.  In FHM1 chromosome 19 has a mutation in the CACNA1A gene.  In FHM2 chromosome 1 has a mutation on the ATP1A2 gene.  In FM3 chromosome 2 has a mutation on SCN1A gene.

Sporadic Hemiplegic Migraine

Sporadic Hemiplegic Migraine (SHM) is a variation of Hemiplegic Migraine.  Unlike Familial Hemiplegic Migraine (FHM), the patient does not have first-degree or second-degree relatives with Hemiplegic Migraine.

 

Diagnosis

This section discusses the Hemiplegic Migraine Diagnosis process.

 

 

 

Symptoms

What are the symptoms of Hemiplegic Migraine?

Symptoms can include visual disturbances, sensory loss, weakness to paralysis on one-side of the body, confusion, speech difficulty, impaired consciousness, coma, memory loss, as well as several other symptoms.

 

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The Hemiplegic Migraine Foundation (HMF) is dedicated to finding a cure for Hemiplegic Migraine, advancing treatments and care, and helping those affected through advocacy, education, research, service, and support.

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